Stem cell-based in vitro models: 
where are we today? 

Human skin stem cell-derived hepatic cells and their potential use in toxicity testing and drug discovery    

STEM-CELL BASED

3D-in vitro models of liver fibrosis 

2PP-printing to create innovative 3D-culture models 

Testicular organoids from primary cells: 
an important step towards human in vitro 
spermatogenesis 

3D-CULTURE

CRISPR/Cas9-based gene editing: an emerging platform for in vitro research 

In silico methods to prioritize potentially genotoxic substances used in food contact materials

Cellular and molecular imaging to reduce and refine animal experiments

Chip for animal-free genotoxicity testing